increased trabecular bone thickness_Grem1<tm1Ecan>/Grem1<tm1Rmh>,Tg(BGLAP-cre)1Clem/0

http://metadb.riken.jp/0009347I129P2OlaHsd129X1SvJC57BL6FVBNGrem1tm1EcanGrem1tm1RmhTgBGLAPcre1Clem0Grem1tm1EcanTgBGLAPcre1ClemGrem1tm1Rmh

increased trabecular bone thickness_Grem1<tm1Ecan>/Grem1<tm1Rmh>,Tg(BGLAP-cre)1Clem/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Thomas L Clemens
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450260
• gremlin 1, DAN family BMP antagonist
  http://metadb.riken.jp/db/mgi_rdf/MGI:1344337

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grem1<tm1Ecan>/Grem1<tm1Rmh>,Tg(BGLAP-cre)1Clem/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grem1<tm1Ecan>|Tg(BGLAP-cre)1Clem|Grem1<tm1Rmh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased trabecular bone thickness
  http://purl.obolibrary.org/obo/MP_0009347

文献

http://purl.org/net/cito/citesAsAuthority

• Elisabetta. Gazzerro, et.al., Conditional deletion of gremlin causes a transient increase in bone formation and bone mass., The Journal of biological chemistry, 2007, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/17785465