abnormal prostate gland ventral lobe morphology_Gt(ROSA)26Sor<tm1(TMPRSS2/ERG)Key>/Gt(ROSA)26Sor<+>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009380I129C57BL6DBA2GtROSA26Sortm1TMPRSS2ERGKeyGtROSA26SorTgPbsncre4Prb0TgPbsncre4PrbGtROSA26SorGtROSA26Sortm1TMPRSS2ERGKey

abnormal prostate gland ventral lobe morphology_Gt(ROSA)26Sor<tm1(TMPRSS2/ERG)Key>/Gt(ROSA)26Sor<+>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(TMPRSS2/ERG)Key>/Gt(ROSA)26Sor<+>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pbsn-cre)4Prb|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(TMPRSS2/ERG)Key>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal prostate gland ventral lobe morphology
  http://purl.obolibrary.org/obo/MP_0009380

文献

http://purl.org/net/cito/citesAsAuthority

• Yu. Chen, et.al., ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss., Nature medicine, 2013, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/23817021