decreased skeletal muscle fiber size_Smn1<tm1Msd>/Smn1<tm1Msd>,Tg(Prnp-SMN)92Ahmb/Tg(Prnp-SMN)92Ahmb,Grm7<Tg(SMN2)89Ahmb>/Grm7<Tg(SMN2)89Ahmb>

http://metadb.riken.jp/0009400I129P2OlaHsdFVBNSmn1tm1MsdSmn1tm1MsdTgPrnpSMN92AhmbTgPrnpSMN92AhmbGrm7TgSMN289AhmbGrm7TgSMN289AhmbTgPrnpSMN92AhmbGrm7TgSMN289AhmbSmn1tm1Msd

decreased skeletal muscle fiber size_Smn1<tm1Msd>/Smn1<tm1Msd>,Tg(Prnp-SMN)92Ahmb/Tg(Prnp-SMN)92Ahmb,Grm7<Tg(SMN2)89Ahmb>/Grm7<Tg(SMN2)89Ahmb>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, metabotropic 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351344
• transgene insertion 92, Arthur H M Burghes
  http://metadb.riken.jp/db/mgi_rdf/MGI:3774942
• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Smn1<tm1Msd>/Smn1<tm1Msd>,Tg(Prnp-SMN)92Ahmb/Tg(Prnp-SMN)92Ahmb,Grm7<Tg(SMN2)89Ahmb>/Grm7<Tg(SMN2)89Ahmb>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-SMN)92Ahmb|Grm7<Tg(SMN2)89Ahmb>|Smn1<tm1Msd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased skeletal muscle fiber size
  http://purl.obolibrary.org/obo/MP_0009400

文献

http://purl.org/net/cito/citesAsAuthority

• Tatiana O. Gavrilina, et.al., Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect., Human molecular genetics, 2008, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/18178576