abnormal nicotine-mediated receptor currents_Chrna7<tm2Bay>/Chrna7<tm2Bay>

http://metadb.riken.jp/0009475I129S7SvEvBrdC57BL6JChrna7tm2BayChrna7tm2BayChrna7tm2Bay

abnormal nicotine-mediated receptor currents_Chrna7<tm2Bay>/Chrna7<tm2Bay>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cholinergic receptor, nicotinic, alpha polypeptide 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:99779

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chrna7<tm2Bay>/Chrna7<tm2Bay>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrna7<tm2Bay>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal nicotine-mediated receptor currents
  http://purl.obolibrary.org/obo/MP_0009475

文献

http://purl.org/net/cito/citesAsAuthority

• A. Orr-Urtreger, et.al., Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth., Journal of neurochemistry, 2000, 74
  http://rdf.ncbi.nlm.nih.gov/pubmed/10800961