decreased thymocyte apoptosis_Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0009542IC57BL6C57BL6JDBA2JTgCd4BCL2G101AD102AD103AAWnt0TgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboTgCd4BCL2G101AD102AD103AAWnt

decreased thymocyte apoptosis_Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559
• transgene insertion A, Astar Winoto
  http://metadb.riken.jp/db/mgi_rdf/MGI:5661470

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thymocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0009542

文献

http://purl.org/net/cito/citesAsAuthority

• Megan L. Burger, et.al., T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity., eLife, 2014, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/25182415