decreased thymocyte apoptosis_Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0,Tg(Nr4a1-EGFP/cre)820Khog/0

http://metadb.riken.jp/0009542IC57BL6C57BL6JTgCd4BCL2G101AD102AD103AAWnt0TgNr4a1EGFPcre820Khog0TgCd4BCL2G101AD102AD103AAWntTgNr4a1EGFPcre820Khog

decreased thymocyte apoptosis_Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0,Tg(Nr4a1-EGFP/cre)820Khog/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 820, Kristin A Hogquist
  http://metadb.riken.jp/db/mgi_rdf/MGI:5007642
• transgene insertion A, Astar Winoto
  http://metadb.riken.jp/db/mgi_rdf/MGI:5661470

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt/0,Tg(Nr4a1-EGFP/cre)820Khog/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt|Tg(Nr4a1-EGFP/cre)820Khog

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased thymocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0009542

文献

http://purl.org/net/cito/citesAsAuthority

• Megan L. Burger, et.al., T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunity., eLife, 2014, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/25182415