decreased platelet aggregation_Pik3cb<tm1Bvan>/Pik3cb<tm1Bvan>,Tg(Pf4-icre)Q3Rsko/0

http://metadb.riken.jp/0009549I129P2OlaHsdPik3cbtm1BvanPik3cbtm1BvanTgPf4icreQ3Rsko0TgPf4icreQ3RskoPik3cbtm1Bvan

decreased platelet aggregation_Pik3cb<tm1Bvan>/Pik3cb<tm1Bvan>,Tg(Pf4-icre)Q3Rsko/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1922019
• transgene insertion Q3, Radek C Skoda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764699

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3cb<tm1Bvan>/Pik3cb<tm1Bvan>,Tg(Pf4-icre)Q3Rsko/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pf4-icre)Q3Rsko|Pik3cb<tm1Bvan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet aggregation
  http://purl.obolibrary.org/obo/MP_0009549

文献

http://purl.org/net/cito/citesAsAuthority

• Valérie. Martin, et.al., Deletion of the p110beta isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/20065293