increased urinary bladder carcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0009550I129P2OlaHsd129S4SvJaeC57BL6FVBPtentm1HwuPtentm1HwuTrp53tm1BrnTrp53tm1BrnPtentm1HwuTrp53tm1Brn

increased urinary bladder carcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased urinary bladder carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009550

文献

http://purl.org/net/cito/citesAsAuthority

• Anna M. Puzio-Kuter, et.al., Inactivation of p53 and Pten promotes invasive bladder cancer., Genes & development, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/19261747