increased urinary bladder carcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Stk11<tm1Keis>/Stk11<tm1Keis>,Tg(Cyp1a1-cre/ERT)1Dwi/0

http://metadb.riken.jp/0009550I129P2OlaHsdC57BL6C57BL6JCBAPtentm2MakPtentm2MakStk11tm1KeisStk11tm1KeisTgCyp1a1creERT1Dwi0Stk11tm1KeisPtentm2MakTgCyp1a1creERT1Dwi

increased urinary bladder carcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Stk11<tm1Keis>/Stk11<tm1Keis>,Tg(Cyp1a1-cre/ERT)1Dwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• serine/threonine kinase 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341870
• transgene insertion 1, Douglas J Winton
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829428

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm2Mak>/Pten<tm2Mak>,Stk11<tm1Keis>/Stk11<tm1Keis>,Tg(Cyp1a1-cre/ERT)1Dwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stk11<tm1Keis>|Pten<tm2Mak>|Tg(Cyp1a1-cre/ERT)1Dwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased urinary bladder carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009550

文献

http://purl.org/net/cito/citesAsAuthority

• Boris Y. Shorning, et.al., Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21283818