increased urinary bladder carcinoma incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Upk2-cre)6Xrw/0

http://metadb.riken.jp/0009550I129S4SvJae129X1SvJFVBNCtnnb1tm1MmtCtnnb1Ptentm1HwuPtentm1HwuTgUpk2cre6Xrw0Ctnnb1Ctnnb1tm1MmtPtentm1HwuTgUpk2cre6Xrw

increased urinary bladder carcinoma incidence_Ctnnb1<tm1Mmt>/Ctnnb1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Upk2-cre)6Xrw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 6, Xue-Ru Wu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3583892
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm1Mmt>/Ctnnb1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Upk2-cre)6Xrw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctnnb1<+>|Ctnnb1<tm1Mmt>|Pten<tm1Hwu>|Tg(Upk2-cre)6Xrw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased urinary bladder carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009550

文献

http://purl.org/net/cito/citesAsAuthority

• I. Ahmad, et.al., β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation., Oncogene, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20818428