urinary bladder obstruction_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Pten<tm1Mro>/Pten<+>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009552I129P2OlaHsdC57BL6DBA2FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorPtentm1MroPtenTgPbsncre4Prb0TgPbsncre4PrbGtROSA26SorGtROSA26Sortm1CAGBmi1EGFPNkiPtentm1MroPten

urinary bladder obstruction_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Pten<tm1Mro>/Pten<+>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Pten<tm1Mro>/Pten<+>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pbsn-cre)4Prb|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>|Pten<tm1Mro>|Pten<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• urinary bladder obstruction
  http://purl.obolibrary.org/obo/MP_0009552

文献

http://purl.org/net/cito/citesAsAuthority

• Karim. Nacerddine, et.al., Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/22505453