acephaly_Dph1<tm2Bhr>/Dph1<+>,Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

http://metadb.riken.jp/0009579I129SSvEv129S4SvJaeC57BL6JCBAJDph1tm2BhrDph1GtROSA26Sortm1DTAJpmbGtROSA26SorTgWnt1cre11Rth0Dph1GtROSA26SorTgWnt1cre11RthDph1tm2BhrGtROSA26Sortm1DTAJpmb

acephaly_Dph1<tm2Bhr>/Dph1<+>,Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• diphthamide biosynthesis 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2151233
• transgene insertion 11, David H Rowitch
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447280

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dph1<tm2Bhr>/Dph1<+>,Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Wnt1-cre)11Rth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dph1<+>|Gt(ROSA)26Sor<+>|Tg(Wnt1-cre)11Rth|Dph1<tm2Bhr>|Gt(ROSA)26Sor<tm1(DTA)Jpmb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * CBA/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• acephaly
  http://purl.obolibrary.org/obo/MP_0009579

文献

http://purl.org/net/cito/citesAsAuthority

• Yi-Ru. Yu, et.al., Role of OVCA1/DPH1 in craniofacial abnormalities of Miller-Dieker syndrome., Human molecular genetics, 2014, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/24895408