abnormal corneocyte envelope morphology_Grhl1<tm1Jane>/Grhl1<tm1Jane>,Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre/ERT)20Efu/0

http://metadb.riken.jp/0009594I129S1SvC57BL6CD1Grhl1tm1JaneGrhl1tm1JaneGrhl3tm1JaneGrhl3tm31JaneTgKRT14creERT20Efu0Grhl3tm31JaneTgKRT14creERT20EfuGrhl3tm1JaneGrhl1tm1Jane

abnormal corneocyte envelope morphology_Grhl1<tm1Jane>/Grhl1<tm1Jane>,Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre/ERT)20Efu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• grainyhead-like 1 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182540
• transgene insertion 20, Elaine Fuchs
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446592
• grainyhead-like 3 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655333

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grhl1<tm1Jane>/Grhl1<tm1Jane>,Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre/ERT)20Efu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grhl3<tm3.1Jane>|Tg(KRT14-cre/ERT)20Efu|Grhl3<tm1Jane>|Grhl1<tm1Jane>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal corneocyte envelope morphology
  http://purl.obolibrary.org/obo/MP_0009594

文献

http://purl.org/net/cito/citesAsAuthority

• Michael. Cangkrama, et.al., Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life., The Journal of investigative dermatology, 2016, 136
  http://rdf.ncbi.nlm.nih.gov/pubmed/26975724