increased skin squamous cell carcinoma incidence_Aicda<tm1(cre)Mnz>/Aicda<+>,Gt(ROSA)26Sor<tm2(sb11)Njen>/Gt(ROSA)26Sor<+>,TgTn(sb-T2/Onc2)6070Njen/0

http://metadb.riken.jp/0009704I129129P2OlaHsdC57BL6C57BL6JAicdatm1creMnzAicdaGtROSA26Sortm2sb11NjenGtROSA26SorTgTnsbT2Onc26070Njen0TgTnsbT2Onc26070NjenGtROSA26SorAicdatm1creMnzGtROSA26Sortm2sb11NjenAicda

increased skin squamous cell carcinoma incidence_Aicda<tm1(cre)Mnz>/Aicda<+>,Gt(ROSA)26Sor<tm2(sb11)Njen>/Gt(ROSA)26Sor<+>,TgTn(sb-T2/Onc2)6070Njen/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279
• transgenic transposon concatemer 6070, Nancy A Jenkins
  http://metadb.riken.jp/db/mgi_rdf/MGI:3613046
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1(cre)Mnz>/Aicda<+>,Gt(ROSA)26Sor<tm2(sb11)Njen>/Gt(ROSA)26Sor<+>,TgTn(sb-T2/Onc2)6070Njen/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• TgTn(sb-T2/Onc2)6070Njen|Gt(ROSA)26Sor<+>|Aicda<tm1(cre)Mnz>|Gt(ROSA)26Sor<tm2(sb11)Njen>|Aicda<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin squamous cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009704

文献

http://purl.org/net/cito/citesAsAuthority

• Adam J. Dupuy, et.al., A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice., Cancer research, 2009, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/19808965