increased skin squamous cell carcinoma incidence_Mmp9<tm1Tvu>/Mmp9<tm1Tvu>,Tg(KRT14-HPV16)wt1Dh/0

http://metadb.riken.jp/0009704I129S6SvEvTacC57BL6DBA2FVBNMmp9tm1TvuMmp9tm1TvuTgKRT14HPV16wt1Dh0TgKRT14HPV16wt1DhMmp9tm1Tvu

increased skin squamous cell carcinoma incidence_Mmp9<tm1Tvu>/Mmp9<tm1Tvu>,Tg(KRT14-HPV16)wt1Dh/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion wt1, Douglas Hanahan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3047399
• matrix metallopeptidase 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:97011

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mmp9<tm1Tvu>/Mmp9<tm1Tvu>,Tg(KRT14-HPV16)wt1Dh/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(KRT14-HPV16)wt1Dh|Mmp9<tm1Tvu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin squamous cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009704

文献

http://purl.org/net/cito/citesAsAuthority

• L M. Coussens, et.al., MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis., Cell, 2000, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/11081634