absent Purkinje cell layer_En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm1Tmj>/Lhx1<tm2.1Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>

http://metadb.riken.jp/0009718I129S1Sv129S7SvEvBrd129X1SvJEn1tm2creWrstEn1Lhx1tm1TmjLhx1tm21BhrLhx5tm1LmgdLhx5tm1LmgdEn1Lhx5tm1LmgdEn1tm2creWrstLhx1tm21BhrLhx1tm1Tmj

absent Purkinje cell layer_En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm1Tmj>/Lhx1<tm2.1Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• LIM homeobox protein 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:107792
• LIM homeobox protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99783
• engrailed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95389

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm1Tmj>/Lhx1<tm2.1Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• En1<+>|Lhx5<tm1Lmgd>|En1<tm2(cre)Wrst>|Lhx1<tm2.1Bhr>|Lhx1<tm1Tmj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent Purkinje cell layer
  http://purl.obolibrary.org/obo/MP_0009718

文献

http://purl.org/net/cito/citesAsAuthority

• Yangu. Zhao, et.al., LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17664423