impaired behavioral response to nicotine_Chrna4<tm1.2Tmcg>/Chrna4<tm1.2Tmcg>

http://metadb.riken.jp/0009756I129SSvEv129S1SvC57BL6Chrna4tm12TmcgChrna4tm12TmcgChrna4tm12Tmcg

impaired behavioral response to nicotine_Chrna4<tm1.2Tmcg>/Chrna4<tm1.2Tmcg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cholinergic receptor, nicotinic, alpha polypeptide 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:87888

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chrna4<tm1.2Tmcg>/Chrna4<tm1.2Tmcg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrna4<tm1.2Tmcg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired behavioral response to nicotine
  http://purl.obolibrary.org/obo/MP_0009756

文献

http://purl.org/net/cito/citesAsAuthority

• Tresa M. McGranahan, et.al., α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21795541