impaired behavioral response to morphine_Oprk1<tm1Kff>/Oprk1<tm1Kff>

http://metadb.riken.jp/0009757I129S2SvPasC57BL6Oprk1tm1KffOprk1tm1KffOprk1tm1Kff

impaired behavioral response to morphine_Oprk1<tm1Kff>/Oprk1<tm1Kff>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opioid receptor, kappa 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97439

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Oprk1<tm1Kff>/Oprk1<tm1Kff>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Oprk1<tm1Kff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired behavioral response to morphine
  http://purl.obolibrary.org/obo/MP_0009757

文献

http://purl.org/net/cito/citesAsAuthority

• F. Simonin, et.al., Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal., The EMBO journal, 1998, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/9463367