impaired behavioral response to morphine_Oprm1<tm1Kff>/Oprm1<tm1Kff>

http://metadb.riken.jp/0009757I129S2SvPasOprm1tm1KffOprm1tm1KffOprm1tm1Kff

impaired behavioral response to morphine_Oprm1<tm1Kff>/Oprm1<tm1Kff>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opioid receptor, mu 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97441

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Oprm1<tm1Kff>/Oprm1<tm1Kff>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Oprm1<tm1Kff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired behavioral response to morphine
  http://purl.obolibrary.org/obo/MP_0009757

文献

http://purl.org/net/cito/citesAsAuthority

• Raphaël. Weibel, et.al., Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/24069332
• A G. Schuller, et.al., Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1., Nature neuroscience, 1999, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/10195199
• H W. Matthes, et.al., Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene., Nature, 1996, 383
  http://rdf.ncbi.nlm.nih.gov/pubmed/8893006