impaired behavioral response to morphine_Oprm1<tm1Jep>/Oprm1<+>

http://metadb.riken.jp/0009757I129SSvEvOprm1tm1JepOprm1Oprm1tm1JepOprm1

impaired behavioral response to morphine_Oprm1<tm1Jep>/Oprm1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opioid receptor, mu 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97441

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Oprm1<tm1Jep>/Oprm1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Oprm1<tm1Jep>|Oprm1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired behavioral response to morphine
  http://purl.obolibrary.org/obo/MP_0009757

文献

http://purl.org/net/cito/citesAsAuthority

• A G. Schuller, et.al., Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1., Nature neuroscience, 1999, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/10195199
• L B. Hough, et.al., Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice., Brain research, 2000, 880
  http://rdf.ncbi.nlm.nih.gov/pubmed/11032994