increased sensitivity to induced morbidity/mortality_Itgb3<tm1Hyn>/Itgb3<tm1Hyn>,Ldlr<tm1Her>/Ldlr<tm1Her>

http://metadb.riken.jp/0009763I129S2SvPas129S7SvEvBrdC57BL6Itgb3tm1HynItgb3tm1HynLdlrtm1HerLdlrtm1HerLdlrtm1HerItgb3tm1Hyn

increased sensitivity to induced morbidity/mortality_Itgb3<tm1Hyn>/Itgb3<tm1Hyn>,Ldlr<tm1Her>/Ldlr<tm1Her>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin beta 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:96612
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb3<tm1Hyn>/Itgb3<tm1Hyn>,Ldlr<tm1Her>/Ldlr<tm1Her>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<tm1Her>|Itgb3<tm1Hyn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009763

文献

http://purl.org/net/cito/citesAsAuthority

• Sherry. Weng, et.al., Beta3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/12746502