increased sensitivity to xenobiotic induced morbidity/mortality_Wwp2<tm1.1Yyiw>/Wwp2<tm1.1Yyiw>

http://metadb.riken.jp/0009766I129SSvEvC57BL6FVBNWwp2tm11YyiwWwp2tm11YyiwWwp2tm11Yyiw

increased sensitivity to xenobiotic induced morbidity/mortality_Wwp2<tm1.1Yyiw>/Wwp2<tm1.1Yyiw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• WW domain containing E3 ubiquitin protein ligase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914144

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Wwp2<tm1.1Yyiw>/Wwp2<tm1.1Yyiw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Wwp2<tm1.1Yyiw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to xenobiotic induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009766

文献

http://purl.org/net/cito/citesAsAuthority

• Yan. Yang, et.al., E3 ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23479606