abnormal retinal development_Atoh7<tm1.1(Ascl1)Nlbr>/Atoh7<+>,Tg(Atoh7-cre)360Gla/0,Tg(CAG-Bgeo/GFP)21Lbe/0

http://metadb.riken.jp/0009772EI129C57BL6FVBNSJLorI129C57BL6CD1FVBNSJLAtoh7tm11Ascl1NlbrAtoh7TgAtoh7cre360Gla0TgCAGBgeoGFP21Lbe0Atoh7TgAtoh7cre360GlaAtoh7tm11Ascl1NlbrTgCAGBgeoGFP21Lbe

abnormal retinal development_Atoh7<tm1.1(Ascl1)Nlbr>/Atoh7<+>,Tg(Atoh7-cre)360Gla/0,Tg(CAG-Bgeo/GFP)21Lbe/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 360, Tom Glaser
  http://metadb.riken.jp/db/mgi_rdf/MGI:5428436
• transgene insertion 21, Corrinne Lobe
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046175
• atonal bHLH transcription factor 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355553

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atoh7<tm1.1(Ascl1)Nlbr>/Atoh7<+>,Tg(Atoh7-cre)360Gla/0,Tg(CAG-Bgeo/GFP)21Lbe/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atoh7<+>|Tg(Atoh7-cre)360Gla|Atoh7<tm1.1(Ascl1)Nlbr>|Tg(CAG-Bgeo/GFP)21Lbe

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129 * C57BL/6 * FVB/N * SJL) or (involves: 129 * C57BL/6 * CD-1 * FVB/N * SJL)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retinal development
  http://purl.obolibrary.org/obo/MP_0009772

文献

http://purl.org/net/cito/citesAsAuthority

• Robert B. Hufnagel, et.al., Heterochronic misexpression of Ascl1 in the Atoh7 retinal cell lineage blocks cell cycle exit., Molecular and cellular neurosciences, 2013, 54
  http://rdf.ncbi.nlm.nih.gov/pubmed/23481413