increased tumor latency_Erbb3<tm1.1(ERBB3)Mul>/Erbb3<+>,Tg(MMTV-Erbb2*)NDL2-5Mul/0

http://metadb.riken.jp/0009828I129P2OlaHsdC57BL6FVBNErbb3tm11ERBB3MulErbb3TgMMTVErbb2NDL25Mul0TgMMTVErbb2NDL25MulErbb3Erbb3tm11ERBB3Mul

increased tumor latency_Erbb3<tm1.1(ERBB3)Mul>/Erbb3<+>,Tg(MMTV-Erbb2*)NDL2-5Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion NDL2-5, William J Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794308
• erb-b2 receptor tyrosine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95411

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Erbb3<tm1.1(ERBB3)Mul>/Erbb3<+>,Tg(MMTV-Erbb2*)NDL2-5Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-Erbb2*)NDL2-5Mul|Erbb3<+>|Erbb3<tm1.1(ERBB3)Mul>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased tumor latency
  http://purl.obolibrary.org/obo/MP_0009828

文献

http://purl.org/net/cito/citesAsAuthority

• Hicham. Lahlou, et.al., Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis., Cancer research, 2012, 72
  http://rdf.ncbi.nlm.nih.gov/pubmed/22665265