decreased neural crest cell number_Ret<tm2(RET)Heno>/Ret<tm2(RET)Jmi>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0009843I129SSvC57BL6CBARettm2RETHenoRettm2RETJmiTgCAGcreEsr15Amc0Rettm2RETJmiRettm2RETHenoTgCAGcreEsr15Amc

decreased neural crest cell number_Ret<tm2(RET)Heno>/Ret<tm2(RET)Jmi>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ret proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97902
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ret<tm2(RET)Heno>/Ret<tm2(RET)Jmi>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ret<tm2(RET)Jmi>|Ret<tm2(RET)Heno>|Tg(CAG-cre/Esr1*)5Amc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased neural crest cell number
  http://purl.obolibrary.org/obo/MP_0009843

文献

http://purl.org/net/cito/citesAsAuthority

• Toshihiro. Uesaka, et.al., Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18414682