abnormal aorta elastic tissue morphology_Efemp2<tm1Dgen>/Efemp2<tm1Dgen>

http://metadb.riken.jp/0009862I129P2OlaHsdC57BL6Efemp2tm1DgenEfemp2tm1DgenEfemp2tm1Dgen

abnormal aorta elastic tissue morphology_Efemp2<tm1Dgen>/Efemp2<tm1Dgen>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• epidermal growth factor-containing fibulin-like extracellular matrix protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891209

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Efemp2<tm1Dgen>/Efemp2<tm1Dgen>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Efemp2<tm1Dgen>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal aorta elastic tissue morphology
  http://purl.obolibrary.org/obo/MP_0009862

文献

http://purl.org/net/cito/citesAsAuthority

• Precious J. McLaughlin, et.al., Targeted disruption of fibulin-4 abolishes elastogenesis and causes perinatal lethality in mice., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16478991
• Masahito. Horiguchi, et.al., Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19855011