abnormal ascending aorta morphology_Agtr1a<tm1Uky>/Agtr1a<tm1Uky>,Ldlr<tm1Her>/Ldlr<tm1Her>,Tg(Tek-cre)12Flv/0

http://metadb.riken.jp/0009867I129S7SvEvBrdC3HC57BL6C57BL6NAgtr1atm1UkyAgtr1atm1UkyLdlrtm1HerLdlrtm1HerTgTekcre12Flv0Agtr1atm1UkyTgTekcre12FlvLdlrtm1Her

abnormal ascending aorta morphology_Agtr1a<tm1Uky>/Agtr1a<tm1Uky>,Ldlr<tm1Her>/Ldlr<tm1Her>,Tg(Tek-cre)12Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• angiotensin II receptor, type 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:87964
• transgene insertion 12, Richard A Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136409

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Agtr1a<tm1Uky>/Agtr1a<tm1Uky>,Ldlr<tm1Her>/Ldlr<tm1Her>,Tg(Tek-cre)12Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Agtr1a<tm1Uky>|Tg(Tek-cre)12Flv|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C3H * C57BL/6 * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal ascending aorta morphology
  http://purl.obolibrary.org/obo/MP_0009867

文献

http://purl.org/net/cito/citesAsAuthority

• Debra L. Rateri, et.al., Endothelial cell-specific deficiency of Ang II type 1a receptors attenuates Ang II-induced ascending aortic aneurysms in LDL receptor-/- mice., Circulation research, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21252156