decreased susceptibility to bone fracture_Lmna<tm7Lgf>/Lmna<+>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>

http://metadb.riken.jp/0009878I129P2OlaHsd129S4SvJaeC57BL6Lmnatm7LgfLmnaZmpste24tm1SgyZmpste24tm1SgyLmnatm7LgfZmpste24tm1SgyLmna

decreased susceptibility to bone fracture_Lmna<tm7Lgf>/Lmna<+>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lamin A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96794
• zinc metallopeptidase, STE24
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890508

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lmna<tm7Lgf>/Lmna<+>,Zmpste24<tm1Sgy>/Zmpste24<tm1Sgy>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lmna<tm7Lgf>|Zmpste24<tm1Sgy>|Lmna<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to bone fracture
  http://purl.obolibrary.org/obo/MP_0009878

文献

http://purl.org/net/cito/citesAsAuthority

• Catherine. Coffinier, et.al., Direct synthesis of lamin A, bypassing prelamin a processing, causes misshapen nuclei in fibroblasts but no detectable pathology in mice., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20439468