abnormal dendritic spine morphology_Pde4b<enu1H>/Pde4b<enu1H>,Tg(Thy1-EGFP)#Jrs/0

http://metadb.riken.jp/0009936IBALBcAnNC3HHeHC57BL6CBAPde4benu1HPde4benu1HTgThy1EGFPJrs0Pde4benu1HTgThy1EGFPJrs

abnormal dendritic spine morphology_Pde4b<enu1H>/Pde4b<enu1H>,Tg(Thy1-EGFP)#Jrs/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphodiesterase 4B, cAMP specific
  http://metadb.riken.jp/db/mgi_rdf/MGI:99557
• transgene insertion, Joshua R Sanes
  http://metadb.riken.jp/db/mgi_rdf/MGI:4941462

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pde4b<enu1H>/Pde4b<enu1H>,Tg(Thy1-EGFP)#Jrs/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pde4b<enu1H>|Tg(Thy1-EGFP)#Jrs

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/cAnN * C3H/HeH * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dendritic spine morphology
  http://purl.obolibrary.org/obo/MP_0009936

文献

http://purl.org/net/cito/citesAsAuthority

• Alexander. McGirr, et.al., Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition., Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/26272049