abnormal dendritic spine morphology_Arpc3<tm1Ssod>/Arpc3<tm1Ssod>,Gt(ROSA)26Sor<tm2(CAG-tdTomato)Fawa>/Gt(ROSA)26Sor<+>,Tg(Thy1-cre/ERT2,-EYFP)VGfng/0

http://metadb.riken.jp/0009936IC57BL6SJLArpc3tm1SsodArpc3tm1SsodGtROSA26Sortm2CAGtdTomatoFawaGtROSA26SorTgThy1creERT2EYFPVGfng0Arpc3tm1SsodGtROSA26SorTgThy1creERT2EYFPVGfngGtROSA26Sortm2CAGtdTomatoFawa

abnormal dendritic spine morphology_Arpc3<tm1Ssod>/Arpc3<tm1Ssod>,Gt(ROSA)26Sor<tm2(CAG-tdTomato)Fawa>/Gt(ROSA)26Sor<+>,Tg(Thy1-cre/ERT2,-EYFP)VGfng/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion V, Guoping Feng
  http://metadb.riken.jp/db/mgi_rdf/MGI:3719904
• actin related protein 2/3 complex, subunit 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928375
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Arpc3<tm1Ssod>/Arpc3<tm1Ssod>,Gt(ROSA)26Sor<tm2(CAG-tdTomato)Fawa>/Gt(ROSA)26Sor<+>,Tg(Thy1-cre/ERT2,-EYFP)VGfng/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Arpc3<tm1Ssod>|Gt(ROSA)26Sor<+>|Tg(Thy1-cre/ERT2,-EYFP)VGfng|Gt(ROSA)26Sor<tm2(CAG-tdTomato)Fawa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dendritic spine morphology
  http://purl.obolibrary.org/obo/MP_0009936

文献

http://purl.org/net/cito/citesAsAuthority

• Il Hwan. Kim, et.al., Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/23554489