abnormal neuron differentiation_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Notch1<tm1Agt>/Notch1<+>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0009937I129C57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeNotch1tm1AgtNotch1TgNescre1Kln0Fbxw7tm11AxbeNotch1tm1AgtNotch1TgNescre1Kln

abnormal neuron differentiation_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Notch1<tm1Agt>/Notch1<+>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• F-box and WD-40 domain protein 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354695
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Notch1<tm1Agt>/Notch1<+>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fbxw7<tm1.1Axbe>|Notch1<tm1Agt>|Notch1<+>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neuron differentiation
  http://purl.obolibrary.org/obo/MP_0009937

文献

http://purl.org/net/cito/citesAsAuthority

• Joerg D. Hoeck, et.al., Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20935640