decreased cerebral cortex pyramidal cell number_Tg(Prnp-TARDBP*Q331K)31Dwc/?

http://metadb.riken.jp/0009974IC3HC57BL6TgPrnpTARDBPQ331K31DwcTgPrnpTARDBPQ331K31Dwc

decreased cerebral cortex pyramidal cell number_Tg(Prnp-TARDBP*Q331K)31Dwc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 31, Don W Cleveland
  http://metadb.riken.jp/db/mgi_rdf/MGI:5825217

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-TARDBP*Q331K)31Dwc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-TARDBP*Q331K)31Dwc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cerebral cortex pyramidal cell number
  http://purl.obolibrary.org/obo/MP_0009974

文献

http://purl.org/net/cito/citesAsAuthority

• Jacqueline C. Mitchell, et.al., Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS., Acta neuropathologica communications, 2015, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/26108367