increased total body fat amount_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Slc17a6<tm2(cre)Lowl>/Slc17a6<+>

http://metadb.riken.jp/0010024I129S4SvJaeSor129S6SvEvTacC57BL6FVBNMc4rtm2LowlMc4rtm2LowlSlc17a6tm2creLowlSlc17a6Mc4rtm2LowlSlc17a6tm2creLowlSlc17a6

increased total body fat amount_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Slc17a6<tm2(cre)Lowl>/Slc17a6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:2156052
• melanocortin 4 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99457

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Slc17a6<tm2(cre)Lowl>/Slc17a6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mc4r<tm2Lowl>|Slc17a6<tm2(cre)Lowl>|Slc17a6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased total body fat amount
  http://purl.obolibrary.org/obo/MP_0010024

文献

http://purl.org/net/cito/citesAsAuthority

• Bhavik P. Shah, et.al., MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus., Proceedings of the National Academy of Sciences of the United States of America, 2014, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/25157144