increased liver cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Nr5a2<tm3.1Sjns>/Nr5a2<tm3.1Sjns>

http://metadb.riken.jp/0010027I129S7SvEvBrdC57BL6JC57BL6NLdlrtm1HerLdlrtm1HerNr5a2tm31SjnsNr5a2tm31SjnsNr5a2tm31SjnsLdlrtm1Her

increased liver cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Nr5a2<tm3.1Sjns>/Nr5a2<tm3.1Sjns>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• nuclear receptor subfamily 5, group A, member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ldlr<tm1Her>/Ldlr<tm1Her>,Nr5a2<tm3.1Sjns>/Nr5a2<tm3.1Sjns>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nr5a2<tm3.1Sjns>|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver cholesterol level
  http://purl.obolibrary.org/obo/MP_0010027

文献

http://purl.org/net/cito/citesAsAuthority

• Sokrates. Stein, et.al., SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport., Cell metabolism, 2014, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/25176150