hypermyelination_Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>/Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0010050IC57BL6SJLGtROSA26Sortm1CAGRhebPfwGtROSA26Sortm1CAGRhebPfwTgNescre1Kln0GtROSA26Sortm1CAGRhebPfwTgNescre1Kln

hypermyelination_Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>/Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>/Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(CAG-Rheb*)Pfw>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hypermyelination
  http://purl.obolibrary.org/obo/MP_0010050

文献

http://purl.org/net/cito/citesAsAuthority

• Jia. Zou, et.al., Rheb1 is required for mTORC1 and myelination in postnatal brain development., Developmental cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21238928