decreased grip strength_Olig2<tm1(cre)Tmj>/Olig2<+>,Smn1<tm1Jme>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/Grm7<Tg(SMN2)89Ahmb>

http://metadb.riken.jp/0010053I129129P2OlaHsdFVBNOlig2tm1creTmjOlig2Smn1tm1JmeSmn1tm1MsdGrm7TgSMN289AhmbGrm7TgSMN289AhmbOlig2tm1creTmjSmn1tm1MsdOlig2Grm7TgSMN289AhmbSmn1tm1Jme

decreased grip strength_Olig2<tm1(cre)Tmj>/Olig2<+>,Smn1<tm1Jme>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/Grm7<Tg(SMN2)89Ahmb>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• survival motor neuron 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109257
• oligodendrocyte transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1355331
• glutamate receptor, metabotropic 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351344

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Olig2<tm1(cre)Tmj>/Olig2<+>,Smn1<tm1Jme>/Smn1<tm1Msd>,Grm7<Tg(SMN2)89Ahmb>/Grm7<Tg(SMN2)89Ahmb>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Olig2<tm1(cre)Tmj>|Smn1<tm1Msd>|Olig2<+>|Grm7<Tg(SMN2)89Ahmb>|Smn1<tm1Jme>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased grip strength
  http://purl.obolibrary.org/obo/MP_0010053

文献

http://purl.org/net/cito/citesAsAuthority

• Gyu-Hwan. Park, et.al., Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20826664