increased circulating creatine kinase level_Ctss<tm1Hap>/Ctss<tm1Hap>,Dmd<mdx>/Dmd<mdx>

http://metadb.riken.jp/0010090I129S2SvPasC57BL10ScSnCtsstm1HapCtsstm1HapDmdmdxDmdmdxDmdmdxCtsstm1Hap

increased circulating creatine kinase level_Ctss<tm1Hap>/Ctss<tm1Hap>,Dmd<mdx>/Dmd<mdx>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cathepsin S
  http://metadb.riken.jp/db/mgi_rdf/MGI:107341
• dystrophin, muscular dystrophy
  http://metadb.riken.jp/db/mgi_rdf/MGI:94909

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctss<tm1Hap>/Ctss<tm1Hap>,Dmd<mdx>/Dmd<mdx>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dmd<mdx>|Ctss<tm1Hap>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/10ScSn

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating creatine kinase level
  http://purl.obolibrary.org/obo/MP_0010090

文献

http://purl.org/net/cito/citesAsAuthority

• Andoria. Tjondrokoesoemo, et.al., Cathepsin S Contributes to the Pathogenesis of Muscular Dystrophy in Mice., The Journal of biological chemistry, 2016, 291
  http://rdf.ncbi.nlm.nih.gov/pubmed/26966179