abnormal retinal blood vessel morphology_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/?,Pdzrn3<tm1.1Saga>/Pdzrn3<tm1.1Saga>,Tg(Pdgfb-icre/ERT2)1Frut/?

http://metadb.riken.jp/0010097I129S1Sv129X1SvJC57BL6C57BL6NCrljCBACBAJNCrljGtROSA26Sortm4ACTBtdTomatoEGFPLuoPdzrn3tm11SagaPdzrn3tm11SagaTgPdgfbicreERT21FrutTgPdgfbicreERT21FrutPdzrn3tm11SagaGtROSA26Sortm4ACTBtdTomatoEGFPLuo

abnormal retinal blood vessel morphology_Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/?,Pdzrn3<tm1.1Saga>/Pdzrn3<tm1.1Saga>,Tg(Pdgfb-icre/ERT2)1Frut/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• PDZ domain containing RING finger 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1933157
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Marcus Fruttiger
  http://metadb.riken.jp/db/mgi_rdf/MGI:3793847

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>/?,Pdzrn3<tm1.1Saga>/Pdzrn3<tm1.1Saga>,Tg(Pdgfb-icre/ERT2)1Frut/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdgfb-icre/ERT2)1Frut|Pdzrn3<tm1.1Saga>|Gt(ROSA)26Sor<tm4(ACTB-tdTomato,-EGFP)Luo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal retinal blood vessel morphology
  http://purl.obolibrary.org/obo/MP_0010097

文献

http://purl.org/net/cito/citesAsAuthority

• Raj N. Sewduth, et.al., The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling., Nature communications, 2014, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/25198863