abnormal synaptic dopamine release_Oprk1<tm2.1Kff>/Oprk1<tm2.1Kff>,Slc6a3<tm1(cre)Xz>/0

http://metadb.riken.jp/0010149I129129S1SvC57BL6Oprk1tm21KffOprk1tm21KffSlc6a3tm1creXz0Slc6a3tm1creXzOprk1tm21Kff

abnormal synaptic dopamine release_Oprk1<tm2.1Kff>/Oprk1<tm2.1Kff>,Slc6a3<tm1(cre)Xz>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opioid receptor, kappa 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97439
• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Oprk1<tm2.1Kff>/Oprk1<tm2.1Kff>,Slc6a3<tm1(cre)Xz>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<tm1(cre)Xz>|Oprk1<tm2.1Kff>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal synaptic dopamine release
  http://purl.obolibrary.org/obo/MP_0010149

文献

http://purl.org/net/cito/citesAsAuthority

• Jonathan M. Ehrich, et.al., Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/26377476