abnormal small intestinal crypt cell proliferation_Vps35<tm1.1Hckn>/Vps35<tm1.1Hckn>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0010157I129P2OlaHsdC57BL6DBA2Vps35tm11HcknVps35tm11HcknTgVilcreERT223Syr0TgVilcreERT223SyrVps35tm11Hckn

abnormal small intestinal crypt cell proliferation_Vps35<tm1.1Hckn>/Vps35<tm1.1Hckn>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• VPS35 retromer complex component
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890467
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vps35<tm1.1Hckn>/Vps35<tm1.1Hckn>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Vps35<tm1.1Hckn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal small intestinal crypt cell proliferation
  http://purl.obolibrary.org/obo/MP_0010157

文献

http://purl.org/net/cito/citesAsAuthority

• Reinoud E A. de Groot, et.al., Retromer dependent recycling of the Wnt secretion factor Wls is dispensable for stem cell maintenance in the mammalian intestinal epithelium., PloS one, 2013, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/24130821