abnormal small intestinal crypt cell proliferation_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0010157I129S4SvJaeBALBcC57BL6JSJLPtentm1HwuPtentm1HwuTgVil1cre997Gum0TgVil1cre997GumPtentm1Hwu

abnormal small intestinal crypt cell proliferation_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-cre)997Gum|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal small intestinal crypt cell proliferation
  http://purl.obolibrary.org/obo/MP_0010157

文献

http://purl.org/net/cito/citesAsAuthority

• Marie-Josée. Langlois, et.al., Epithelial phosphatase and tensin homolog regulates intestinal architecture and secretory cell commitment and acts as a modifier gene in neoplasia., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/19168705