decreased mammary gland epithelial cell proliferation_Gt(ROSA)26Sor<tm2(CAG-Dsred2/EGFP)Luo>/Gt(ROSA)26Sor<tm1(Notch3*)Sfr>,Notch3<tm1.1(cre/ERT2)Sat>/Notch3<+>

http://metadb.riken.jp/0010174I129S1Sv129X1SvJC57BL6NTacGtROSA26Sortm2CAGDsred2EGFPLuoGtROSA26Sortm1Notch3SfrNotch3tm11creERT2SatNotch3Notch3tm11creERT2SatNotch3GtROSA26Sortm1Notch3SfrGtROSA26Sortm2CAGDsred2EGFPLuo

decreased mammary gland epithelial cell proliferation_Gt(ROSA)26Sor<tm2(CAG-Dsred2/EGFP)Luo>/Gt(ROSA)26Sor<tm1(Notch3*)Sfr>,Notch3<tm1.1(cre/ERT2)Sat>/Notch3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• notch 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:99460

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(CAG-Dsred2/EGFP)Luo>/Gt(ROSA)26Sor<tm1(Notch3*)Sfr>,Notch3<tm1.1(cre/ERT2)Sat>/Notch3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Notch3<tm1.1(cre/ERT2)Sat>|Notch3<+>|Gt(ROSA)26Sor<tm1(Notch3*)Sfr>|Gt(ROSA)26Sor<tm2(CAG-Dsred2/EGFP)Luo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mammary gland epithelial cell proliferation
  http://purl.obolibrary.org/obo/MP_0010174

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel. Lafkas, et.al., Notch3 marks clonogenic mammary luminal progenitor cells in vivo., The Journal of cell biology, 2013, 203
  http://rdf.ncbi.nlm.nih.gov/pubmed/24100291