decreased lung tumor incidence_Kras<tm3Tyj>/Kras<+>,Pik3ca<tm1Jdo>/Pik3ca<tm1Jdo>

http://metadb.riken.jp/0010267I129S4SvJae129S7SvEvBrdC57BL6JKrastm3TyjKrasPik3catm1JdoPik3catm1JdoKrasPik3catm1JdoKrastm3Tyj

decreased lung tumor incidence_Kras<tm3Tyj>/Kras<+>,Pik3ca<tm1Jdo>/Pik3ca<tm1Jdo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1206581
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm3Tyj>/Kras<+>,Pik3ca<tm1Jdo>/Pik3ca<tm1Jdo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Pik3ca<tm1Jdo>|Kras<tm3Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased lung tumor incidence
  http://purl.obolibrary.org/obo/MP_0010267

文献

http://purl.org/net/cito/citesAsAuthority

• Surbhi. Gupta, et.al., Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice., Cell, 2007, 129
  http://rdf.ncbi.nlm.nih.gov/pubmed/17540175