decreased lymphoma incidence_Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>,Tacc3<tm1.1Tno>/Tacc3<tm1.2Tno>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0010268I129S2SvPas129S4SvJaeC57BL6GtROSA26Sortm1creERT2TyjGtROSA26SorTacc3tm11TnoTacc3tm12TnoTrp53tm1TyjTrp53tm1TyjGtROSA26Sortm1creERT2TyjTacc3tm11TnoTacc3tm12TnoGtROSA26SorTrp53tm1Tyj

decreased lymphoma incidence_Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>,Tacc3<tm1.1Tno>/Tacc3<tm1.2Tno>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming, acidic coiled-coil containing protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341163
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>/Gt(ROSA)26Sor<+>,Tacc3<tm1.1Tno>/Tacc3<tm1.2Tno>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(cre/ERT2)Tyj>|Tacc3<tm1.1Tno>|Tacc3<tm1.2Tno>|Gt(ROSA)26Sor<+>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased lymphoma incidence
  http://purl.obolibrary.org/obo/MP_0010268

文献

http://purl.org/net/cito/citesAsAuthority

• R. Yao, et.al., Disruption of Tacc3 function leads to in vivo tumor regression., Oncogene, 2012, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21685933