decreased mammary gland tumor incidence_Itgb1<tm1Mll>/Itgb1<tm1Mll>,Tg(MMTV-cre)7Mul/0,Tg(MMTV-PyVT)634Mul/0

http://metadb.riken.jp/0010269I129X1SvJFVBNItgb1tm1MllItgb1tm1MllTgMMTVcre7Mul0TgMMTVPyVT634Mul0TgMMTVcre7MulItgb1tm1MllTgMMTVPyVT634Mul

decreased mammary gland tumor incidence_Itgb1<tm1Mll>/Itgb1<tm1Mll>,Tg(MMTV-cre)7Mul/0,Tg(MMTV-PyVT)634Mul/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 7, William J Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:3589277
• transgene insertion 634, William Muller
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679594
• integrin beta 1 (fibronectin receptor beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96610

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb1<tm1Mll>/Itgb1<tm1Mll>,Tg(MMTV-cre)7Mul/0,Tg(MMTV-PyVT)634Mul/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(MMTV-cre)7Mul|Itgb1<tm1Mll>|Tg(MMTV-PyVT)634Mul

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mammary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010269

文献

http://purl.org/net/cito/citesAsAuthority

• Donald E. White, et.al., Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction., Cancer cell, 2004, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/15324699