increased melanoma incidence_Cdkn2a<tm1Nesh>/Cdkn2a<tm1Nesh>,X/Tg(Tyr-HRAS)60Lc

http://metadb.riken.jp/0010275I129S6SvEvTacC57BL6JCBAJFVBCdkn2atm1NeshCdkn2atm1NeshXTgTyrHRAS60LcTgTyrHRAS60LcCdkn2atm1Nesh

increased melanoma incidence_Cdkn2a<tm1Nesh>/Cdkn2a<tm1Nesh>,X/Tg(Tyr-HRAS)60Lc

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 60, Lynda Chin
  http://metadb.riken.jp/db/mgi_rdf/MGI:2675988
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Nesh>/Cdkn2a<tm1Nesh>,X/Tg(Tyr-HRAS)60Lc

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tyr-HRAS)60Lc|Cdkn2a<tm1Nesh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * CBA/J * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased melanoma incidence
  http://purl.obolibrary.org/obo/MP_0010275

文献

http://purl.org/net/cito/citesAsAuthority

• Norman Edward. Sharpless, et.al., Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo., Oncogene, 2003, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/12902988