increased astrocytoma incidence_Nf1<tm1Tyj>/?,Trp53<tm1Tyj>/?,Mastr<C57BL/6J>/?

http://metadb.riken.jp/0010277I129S2SvPas129S4SvJaeC57BL6JNf1tm1TyjTrp53tm1TyjMastrC57BL6JNf1tm1TyjTrp53tm1TyjMastrC57BL6J

increased astrocytoma incidence_Nf1<tm1Tyj>/?,Trp53<tm1Tyj>/?,Mastr<C57BL/6J>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• modifier of astrocytoma
  http://metadb.riken.jp/db/mgi_rdf/MGI:3497710
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf1<tm1Tyj>/?,Trp53<tm1Tyj>/?,Mastr<C57BL/6J>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nf1<tm1Tyj>|Trp53<tm1Tyj>|Mastr<C57BL/6J>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased astrocytoma incidence
  http://purl.obolibrary.org/obo/MP_0010277

文献

http://purl.org/net/cito/citesAsAuthority

• Karlyne M. Reilly, et.al., Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15319471