increased glioma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(NES-TVA)J12Ech/0

http://metadb.riken.jp/0010278I129C57BL6FVBNSJLCdkn2atm1RdpCdkn2aTgNESTVAJ12Ech0TgNESTVAJ12EchCdkn2atm1RdpCdkn2a

increased glioma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(NES-TVA)J12Ech/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738
• transgene insertion J12, Eric C Holland
  http://metadb.riken.jp/db/mgi_rdf/MGI:3619221

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(NES-TVA)J12Ech/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(NES-TVA)J12Ech|Cdkn2a<tm1Rdp>|Cdkn2a<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased glioma incidence
  http://purl.obolibrary.org/obo/MP_0010278

文献

http://purl.org/net/cito/citesAsAuthority

• E C. Holland, et.al., A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice., Genes & development, 1998, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/9851974