increased glioma incidence_Tg(NES-TVA)J12Ech/0,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0010278I129C57BL6FVBNTgNESTVAJ12Ech0Trp53tm1BrdTrp53TgNESTVAJ12EchTrp53Trp53tm1Brd

increased glioma incidence_Tg(NES-TVA)J12Ech/0,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion J12, Eric C Holland
  http://metadb.riken.jp/db/mgi_rdf/MGI:3619221
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(NES-TVA)J12Ech/0,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(NES-TVA)J12Ech|Trp53<+>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased glioma incidence
  http://purl.obolibrary.org/obo/MP_0010278

文献

http://purl.org/net/cito/citesAsAuthority

• E C. Holland, et.al., A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice., Genes & development, 1998, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/9851974