increased glioma incidence_Nf1<tm1Fcr>/Nf1<tm1Fcr>,Trp53<tm1Elee>/Trp53<tm1Elee>,Tg(GFAP-cre)25Mes/0

http://metadb.riken.jp/0010278I129SSvEv129S4SvJaeFVBNNf1tm1FcrNf1tm1FcrTrp53tm1EleeTrp53tm1EleeTgGFAPcre25Mes0Trp53tm1EleeNf1tm1FcrTgGFAPcre25Mes

increased glioma incidence_Nf1<tm1Fcr>/Nf1<tm1Fcr>,Trp53<tm1Elee>/Trp53<tm1Elee>,Tg(GFAP-cre)25Mes/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306
• transgene insertion 25, Albee Messing
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179047

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf1<tm1Fcr>/Nf1<tm1Fcr>,Trp53<tm1Elee>/Trp53<tm1Elee>,Tg(GFAP-cre)25Mes/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Elee>|Nf1<tm1Fcr>|Tg(GFAP-cre)25Mes

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased glioma incidence
  http://purl.obolibrary.org/obo/MP_0010278

文献

http://purl.org/net/cito/citesAsAuthority

• Yuan. Wang, et.al., Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19477430